相关实验视频
Updated: Jun 25, 2025

A Porcine Model of Acute Autologous Pulmonary Embolism
Published on: September 6, 2024
在肺栓塞的男性中血清前列腺特异性抗原水平的升高
You-Fan Peng1, Li-Ya Ma1, Miao Luo2
1Department of Respiratory and Critical Care Medicine, Affiliated Hospital of Youjiang Medical University for Nationalities, Baise, China.
肺栓塞 (PE) 与男性的前列腺特异抗原 (tPSA) 水平升高有关. 这一发现表明,在使用tPSA进行前列腺疾病查时,应谨慎使用tPSA.
科学领域:
- 心脏病学 心脏病学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 肺部病理学 肺部病理学
背景情况:
- 低氧症是肺栓塞 (PE) 的标志,与血清前列腺特异抗原 (PSA) 水平的改变有关.
- PE和PSA之间的关系需要进一步调查临床影响.
研究的目的:
- 在被诊断患有PE的男性患者中检查血清总PSA (tPSA) 和自由PSA (fPSA) 水平.
- 评估PSA水平与肺栓塞的严重程度之间的相关性.
主要方法:
- 来自61名PE男性患者和113名年龄匹配的健康对照患者的临床数据的回顾性分析.
- 肺动脉阻塞指数 (PAOI) 用于量化栓塞负担.
- 血清tPSA和fPSA水平在不同组之间的比较以及与PAOI的相关性.
主要成果:
- 与健康对照组相比,患有PE的患者的血清tPSA水平显着更高 (P=.003).
- 在PE患者中,fPSA/tPSA的比率明显较低 (P<.001),而fPSA水平没有差异.
- 血清tPSA水平显示在PE患者中与PAOI具有显著的积极关联 (P=.036),通过多变量分析 (P=.003) 独立证实.
结论:
- 肺栓塞与血清tPSA水平升高有关.
- 血清fPSA水平不受PE的显著影响.
- 在PE患者中进行前列腺疾病查的PSA检测需要谨慎解释,因为PE可能会增加.
更多相关视频
12:13Sequencing Small Non-coding RNA from Formalin-fixed Tissues and Serum-derived Exosomes from Castration-resistant Prostate Cancer Patients
Published on: November 19, 2019
07:57Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
Published on: October 25, 2024
相关概念视频
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme...
Treatment for Pulmonary Arterial Hypertension: Phosphodiesterase Inhibitors
Among the PDE5 inhibitors, sildenafil (Revatio) stands out as a competitive and selective inhibitor. It operates by elevating cellular levels of cGMP and augmenting signaling through the cGMP-PKG pathway, promoting vasodilation. Upon oral...
Treatment for Pulmonary Arterial Hypertension: Prostacyclin Receptor Agonists
These agonists bind to the IPR receptor situated on the plasma membrane of the pulmonary artery smooth muscle cells. This binding triggers a cascade of reactions known as the GS-AC-cAMP-PKA pathway. This pathway results in the relaxation of smooth muscle...
Pulmonary Hypertension: Classification and Pathogenesis
There are various classifications for PH, each relating to different underlying causes and also...
Disorders of the Male Reproductive System
Prostate disorders are another major concern. These conditions can impair urinary flow due to the prostate's location around the urethra....
Radiological Investigation III: Pulmonary Angiogram and PET Scan
Pulmonary Angiogram
A Pulmonary Angiogram is an invasive procedure involving injecting a contrast medium through a catheter threaded into the pulmonary artery or the right side of the heart to visualize the pulmonary vasculature. Computed Tomography (CT) scans have mainly replaced this...