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Updated: Jun 25, 2025

A Familial Hypercholesterolemia Human Liver Chimeric Mouse Model Using Induced Pluripotent Stem Cell-derived Hepatocytes
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多基因背景对家族性高胆固醇血症的临床表现的影响

Mark Trinder1, Lubomira Cermakova1, Isabelle Ruel2

  • 1Centre for Heart Lung Innovation, University of British Columbia and St. Paul's Hospital, Vancouver, Canada (M.T., L.C., L.R.B.).

Arteriosclerosis, thrombosis, and vascular biology
|May 23, 2024
PubMed
概括

冠状动脉疾病 (CAD) 和LDL-C的多原风险评分 (PRS) 影响家族性高胆固醇血症 (FH) 的严重程度. 这些遗传因素可能有助于预测FH患者心血管疾病风险.

关键词:
生物标本银行 生物标本银行心血管疾病心血管疾病胆固醇,LDL 胆固醇,LDL 胆固醇,LDL 胆固醇,LDL 胆固醇冠状动脉疾病是一种冠状动脉疾病.遗传风险评分 遗传风险评分

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