相关实验视频

Updated: Jun 25, 2025

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Author Spotlight: Anterior HR-OCT as a Non-Invasive Tool for Characterizing Ocular Surface Squamous Neoplasia

Published on: August 9, 2024

三维前段光学连贯断层扫描在检测角度关闭的诊断能力

Sunee Chansangpetch^1,2,3, Phichayut Phinyo^1,4, Jayanton Patumanond³

¹Department of Ophthalmology, Faculty of Medicine, Chulalongkorn University and King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok.

Journal of glaucoma

|May 23, 2024

概括

三维 (3D) 角度参数在检测角度关闭方面表现出色. 然而,某些二维 (2D) 水平参数提供了可比的诊断准确性,表明了更简单的临床应用的潜力.

科学领域:

眼科医生眼科眼科
解剖成像解剖成像解剖成像
青光眼的诊断青光眼的诊断

背景情况:

视角闭眼 (angle closure glaucoma) 是导致视力丧失的重要原因之一.
准确检测角度闭合对于及时干预至关重要.
前段光学连贯断层扫描 (AS-OCT) 是一个关键的成像模式.

研究的目的:

为了比较2D水平与3D角度参数的诊断性能,这些参数是从扫描源AS-OCT (CASIA2) 来获得的,用于探测角度闭合.
评估新的3D角度参数及其切割值.

主要方法:

一项横截面研究包括118名发病患者 (59个开放,59个闭合角度).
角度开口距离 (AOD),角度隙面积 (ARA) 和状虹膜空间面积 (TISA) 在距离状突起的250,500和750微米处使用360度半径扫描进行测量.
3D参数被分析为平均值和估计的表面/体积,然后与使用接收器操作特征曲线 (AUC) 的2D水平参数进行比较.

主要成果:

在估计的3D AOD参数 (AOD-500估计3D:AUC 0.950;AOD-750估计3D:AUC 0.948) 观察到的最高诊断性能.
与其二维对应物相比,3D参数显著改善了ARA-250和TISA-250的AUC (P < 0.02).
对于AOD-250或500/750微米的参数,没有发现明显的AUC改善;几个2D和3D参数显示了相似的高性能.

结论:

拟议的3D角度参数证明了对角关闭检测的优秀诊断性能.
尽管3D参数的高性能,某些2D水平测量 (TISA-750,AOD-750,AOD-500) 实现类似的诊断准确度.
在某些测量中,3D分析对优化的2D水平参数的增量好处可能是有限的.

更多相关视频

Doppler Optical Coherence Tomography of Retinal Circulation

Doppler Optical Coherence Tomography of Retinal Circulation

Published on: September 18, 2012

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Assessing Early Stage Open-Angle Glaucoma in Patients by Isolated-Check Visual Evoked Potential

Published on: May 25, 2020

相关概念视频

Angle Closure Glaucoma: Treatment

Angle Closure Glaucoma: Treatment

Angle-closure glaucoma, or closed-angle glaucoma, is an eye condition where the iris bulges out and blocks the iridocorneal angle, resulting in a buildup of aqueous humor and increased intraocular pressure. Immediate medical attention is necessary due to the sudden onset of symptoms. The treatment for angle-closure glaucoma includes short-term and long-term approaches. Short-term treatment involves using eye drops like pilocarpine to lower intraocular pressure by increasing aqueous humor...

Open Angle Glaucoma: Treatment

Open Angle Glaucoma: Treatment

In open-angle glaucoma, the iridocorneal angle remains open, but the trabecular meshwork becomes stiff, slowing down the outflow of aqueous humor. This causes a buildup of aqueous humor in the anterior chamber, leading to a sudden increase in intraocular pressure. The treatment for open-angle glaucoma focuses on reducing the elevated intraocular pressure by either decreasing the secretion of aqueous humor or increasing its outflow.
Drugs such as carbonic anhydrase inhibitors, α2- and...

Glaucoma: Overview

Glaucoma: Overview

Glaucoma is an eye condition characterized by increased intraocular pressure that damages the retina and optic nerve, leading to irreversible blindness if left untreated. The human eye has various components, including the cornea, iris, pupil, lens, and optic nerve. Aqueous humor is secreted by the epithelium of the ciliary body in the posterior chamber and flows through the trabecular meshwork and canal of Schlemm, maintaining normal intraocular pressure. The trabecular meshwork and the canal...