改性活性炭材料辅助的电化学消毒有效地使抗生素耐药细菌失活
Chenxi Zhang1, Jingze Peng1, Shuai Zhang1
1Jiangsu Key Laboratory of Atmospheric Environment Monitoring and Pollution Control (AEMPC), Collaborative Innovation Center of Atmospheric Environment and Equipment Technology (CIC-AEET), School of Environmental Science and Engineering, Nanjing University of Information Science & Technology, Nanjing, People's Republic of China.
改性活性炭材料辅助的电化学消毒 (ED) 有效地使抗生素耐药细菌 (ARB) 失活. 这种环保方法可以实现显著的ARB去除,并防止再生长,为公众健康提供了一个有前途的替代方案.
科学领域:
- 环境科学 环境科学
- 微生物学 微生物学
- 电化学 电化学 电化学
背景情况:
- 抗生素耐药细菌 (ARB) 是一个重大的全球健康挑战.
- 电化学消毒 (ED) 是一种新兴的环保技术,用于非活性化ARB.
研究的目的:
- 为了研究改性活性炭材料 (MACM) 辅助ED对多ARB失活的疗效.
- 评估MACM辅助ED系统的再生能力.
- 通过MACM辅助的ED来阐明ARB的失活机制.
主要方法:
- 在电化学消毒 (ED) 装置中使用改性活性炭材料 (MACM).
- 应用了2.5V的电压进行处理.
- 通过日志减少量化ARB去除.
- 分析了反应性物种和反应性氧物种的生成.
- 在治疗后评估ARB再生.
主要成果:
- 在MACM的帮助下,ED在30分钟内实现了多抗性ARB的5个日志的去除.
- 没有观察到ARB的再生,这表明永久不活化.
- 在ARB中,MACM的电解诱导了高水平的活性,导致氧化应激和细胞膜损伤.
结论:
- 由MACM辅助的ED是一种高效的ARB无活化方法.
- 该机制涉及反应性诱导的氧化应激和细胞膜损伤.
- 这项技术显示出作为控制ARB传播的传统消毒方法的可持续替代方案的前景.
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