结直肠癌手术后肺部并发症的危险因素:一项日本多中心研究
Tetsuro Tominaga1, Takashi Nonaka2, Yuma Takamura2
1Department of Surgical Oncology, Nagasaki University Graduate School of Biomedical Science, 1-7-1 Sakamoto, Nagasaki, 852-8501, Japan. tetsuro.tominaga@nagasaki-u.ac.jp.
International journal of colorectal disease
|May 23, 2024
概括
结直肠手术后的肺部并发症是由男性性别,年龄较大,体重不足和表现较差预测的. 实施康复和肺炎控制可以减轻高风险患者的风险.
科学领域:
- 手术瘤学手术瘤学
- 肺部医学 肺部医学
- 关键的护理关键的护理
背景情况:
- 结直肠手术后的肺部并发症 (PC) 具有显著的死亡率.
- 结直肠手术后PC的危险因素仍未得到充分研究.
- 这项研究解决了在结直肠癌患者中识别PC的预测因子的需要.
研究的目的:
- 调查结直肠癌手术后肺部并发症 (PC) 的发生率和特征.
- 确定与PC发展相关的独立风险因素.
- 为高风险个体制定有针对性的预防策略.
主要方法:
- 在2016年至2022年期间,对3979名接受结直肠癌手术的患者进行了回顾性评估.
- 开发PC的患者 (n=54) 和没有PC的患者 (n=3925) 之间的临床和病理特征的比较.
- 多变量分析以确定PC的独立预测因素.
主要成果:
- PC的发病率为1.5% (54名患者),受影响者死亡率为3.7%.
- PC的独立预测因素包括男性性别,年龄较大,体重不足状态和美国麻醉学会 (ASA-PS) 较差的身体状况.
- 患有PC的患者表现出更高的慢性阻塞性肺病率,更差的表现状况,开放式手术和更大的血液损失.
结论:
- 男性性别,老年,体重不足和ASA-PS不良是PC结肠直肠后手术的重要风险因素.
- 建议进行手术前和手术后的康复计划.
- 应在高风险患者队伍中实施加强的肺炎控制措施.
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