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双边深度听力损失儿童的静脉障碍和姿势发育

Sylvette R Wiener-Vacher^1,2, Marta Campi¹, Simona Caldani^1,2

¹Institut de l'Audition, Institut Pasteur, Centre De Recherche et d'Innovation et Audiologie Humaine (CERIAH), Paris, France.

JAMA network open

|May 23, 2024

概括

在患有严重听力损失 (HL) 的儿童中,尤其是那些有遗传或CMV相关原因的儿童中,静脉功能障碍很常见. 这种损伤与运动发育的延迟有关,突出显示在耳植入之前需要进行前庭评估.

科学领域:

儿科听力学儿科听力学
神经科学是一个神经科学.
发育儿科发育儿科

背景情况:

儿童的深度听力损失 (HL) 可能会影响耳植入物结果,特别是伴随着前庭功能障碍时.
静脉功能评估并非常规地与听力学测试一起用于耳植入决策.

研究的目的:

根据听力损失的起源分类,确定深度HL儿童前庭功能障碍的患病率.
在这个人群中调查前庭功能障碍和延迟的姿势运动发育之间的关联.

主要方法:

一项队列研究分析了592名患有深层HL的儿童进行耳植入的医疗记录.
根据前庭功能分组儿童:正常 (NVF),部分损伤 (PVF) 和完全双边损失 (CBVL).
统计模型评估了HL起源,前庭功能障碍和发展里程碑的实现之间的联系.

主要成果:

在44.4%的儿童中发现了静脉功能障碍,遗传综合征HL (78.3%) 和CMV感染 (69.2%) 的儿童患病率更高.
部分受损或完全双侧前庭损失的儿童显示,延迟运动发育里程碑的几率明显更高.
前庭功能障碍的严重程度与实现里程碑的延迟相关,比如头部持有和走路.

结论:

静脉功能障碍在患有深度HL的儿童中普遍存在,并与运动发育延迟有关.
HL起源影响前庭功能障碍,遗传和CMV相关的原因显示出更高的发病率.
建议在耳植入前进行全面的前庭评估,以指导早期,量身定制的干预措施.

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