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相关概念视频

Electron Microscope Tomography and Single-particle Reconstruction01:07

Electron Microscope Tomography and Single-particle Reconstruction

Transmission electron microscopy (TEM) can be used to determine the 3D structure of biological samples with the help of techniques such as electron microscope tomography and single-particle reconstruction. While single-particle reconstruction can examine macromolecules and macromolecular complexes in vitro conditions only, tomography permits the study of cell components or small cells in vivo.
Electron Tomography
Electron tomography can be performed either in TEM or STEM (scanning transmission...
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Magnetic resonance imaging (MRI) is a noninvasive medical imaging technique based on a phenomenon of nuclear physics discovered in the 1930s, in which matter exposed to magnetic fields and radio waves was found to emit radio signals. In 1970, a physician and researcher named Raymond Damadian noticed that malignant (cancerous) tissue gave off different signals than normal body tissue. He applied for a patent for the first MRI scanning device in clinical use by the early 1980s. The early MRI...

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基于序列扫描的单维多维系统矩阵校准,用于开放侧磁粒子成像.

Jie He, Haoran Zhang, Yimeng Li

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    一种新的校准方法,即基于序列扫描的单维多声元校准 (SS-SDMVC),显著加快了对开放面磁粒子成像 (OS-MPI) 的系统矩阵校准. 这种技术提高了图像重建质量,并减少了测量时间.

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    科学领域:

    • 医疗成像医学成像
    • 生物医学工程 生物医学工程
    • 物理 物理学 物理

    背景情况:

    • 开放式磁粒子成像 (OS-MPI) 显示出干预程序的前景.
    • 目前的OS-MPI系统矩阵校准方法很慢,信号噪声比率 (SNR) 很低.
    • 这些局限性阻碍了OS-MPI.中的基于系统矩阵的实际系统重建.

    研究的目的:

    • 为OS-MPI开发一种高效和高SNR的系统矩阵校准方法.
    • 为了应对在连续扫描中耗时校准和低SNR的挑战.
    • 为了提高基于OS-MPI的系统矩阵重建的可行性.

    主要方法:

    • 引入了基于顺序扫描的单维多声元校准 (SS-SDMVC).
    • 在圆柱形视野 (FOV) 中实现SS-SDMVC,使用移动杆校准样本.
    • 通过标准图像重建验证了SS-SDMVC的可行性,并分析了对噪声和扫描器缺陷的稳定性.

    主要成果:

    • 与传统方法相比,SS-SDMVC显著减少了210.94的测量次数.
    • 在实验性比较中实现了更高的重建质量.
    • 通过模拟,证明了基于SS-SDMVC的重建的稳定性.

    结论:

    • 在OS-MPI中,SS-SDMVC为系统矩阵校准提供了高效和有效的解决方案.
    • 该方法提高了重建质量,减少了校准时间.
    • 预计SS-SDMVC将增强OS-MPI扫描仪,特别是用于人体规模或高梯度应用.