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Updated: Jun 25, 2025

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在SARS-CoV-2中,ORF8调节肺炎和临床疾病进展

Marisa E McGrath1, Yong Xue2, Louis Taylor1

  • 1Center for Pathogen Research, Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, Maryland, United States of America.

PLoS pathogens
|May 23, 2024
PubMed
概括

SARS-CoV-2 附加蛋白 ORF8 对于调节宿主炎症反应至关重要. 缺乏ORF8或具有突变的病毒在小鼠中显示出COVID-19病原体和疾病严重程度的改变.

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