癌症患者和癌症幸存者失眠的干预措施-全面的系统审查和元分析
Eva Rames Nissen1, Henrike Neumann1, Sofie Møgelberg Knutzen1
1Unit for Psychooncology and Health Psychology, Department of Oncology Aarhus University Hospital, and Department of Psychology, Aarhus University, Aarhus, Denmark.
失眠的认知行为疗法 (CBT-I) 是癌症幸存者的失眠最有效的治疗方法,改善睡眠,疲劳和情绪. 简要的CBT-I对那些正在接受活跃癌症治疗的人来说也很有前途.
科学领域:
- 在瘤学瘤学.
- 睡眠医学 睡眠医学
- 心理学 心理学 心理学
背景情况:
- 失眠在癌症患者和癌症幸存者中非常普遍.
- 对这一群体需要有效的管理策略.
研究的目的:
- 对成人癌症患者和癌症幸存者的失眠干预措施的有效性进行系统审查和元分析.
- 为了比较药理和非药理治疗.
主要方法:
- 按照PRISMA指南进行的61项随机对照试验 (6528名参与者) 的系统审查和元分析.
- 包括药物,身体和心理干预.
- 使用频率主义和贝叶斯方法分析失眠严重程度和二次睡眠/不睡眠结果.
主要成果:
- 失眠的认知行为疗法 (CBT-I) 在减少癌症幸存者的失眠严重程度,疲劳,抑郁和焦虑方面表现出最高的疗效.
- CBT-I显示了干预后 (g=0.86) 的很大影响和随访后 (g=0.55) 的中等影响.
- 其他干预措施,如光疗,睡眠药物,黑激素,运动,心身和正念疗法,显示了一些好处,但不如CBT-I那么令人信服. 简要的CBT-I是积极治疗患者的一个有希望的替代方案.
结论:
- CBT-I是癌症幸存者失眠的第一线治疗方法,对睡眠和非睡眠结果产生积极影响.
- 不那么密集的干预措施显示出潜力.
- 需要进一步研究癌症患者和癌症幸存者的睡眠障碍.
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