在2019年冠状病毒疾病 (COVID-19) 之后的绝经后出血 疫苗接种:疫苗不良事件报告系统
Penelope Strid1, Winston E Abara, Elizabeth Clark
1COVID-19 Response Team, Centers for Disease Control and Prevention, Atlanta, Georgia.
Obstetrics and gynecology
|May 23, 2024
概括
在COVID-19疫苗接种后报告的绝经后出血事件很少见. 经过验证的病例不常见,原因与已知的绝经后出血因素一致,这表明没有新的安全问题.
科学领域:
- 疫苗学 疫苗学 疫苗学
- 妇科 妇科 妇科 妇科
- 公共卫生 公共卫生
背景情况:
- 疫苗不良事件报告系统 (VAERS) 监测美国疫苗的安全性.
- 绝经后出血 (PMB) 是50岁以上女性的妇科问题.
- 了解COVID-19疫苗接种后的潜在不良事件至关重要.
研究的目的:
- 调查COVID-19疫苗接种后发生的绝经后出血报告的发生情况.
- 评估这些报告事件的频率和特征.
主要方法:
- 对2020年12月13日至2021年12月13日的美国VAERS数据进行回顾性分析.
- 在COVID-19疫苗接种者中识别和验证绝经后出血报告.
- 计算每100万个50岁以上接种疫苗的女性中事件率.
主要成果:
- 在711,224份COVID-19疫苗接种报告中,发现了554份可能的PMB报告.
- 检查了434份报告,估计每100万接种疫苗的妇女 (50岁以上) 均有7份经过验证的PMB报告.
- 经过验证的PMB的原因与已确定的病因因素一致.
结论:
- 接种COVID-19疫苗后的绝经后出血是一个罕见的事件.
- 发病率和报告的原因并不表明有新的关联.
- 这些发现支持COVID-19疫苗在PMB方面的安全性.
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