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Updated: May 1, 2026

DNA Methylation: Bisulphite Modification and Analysis
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DNA Methylation: Bisulphite Modification and Analysis

Published on: October 21, 2011

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用于分析甲基化测序数据的可变系数模型

Katarzyna Górczak1, Tomasz Burzykowski2, Jürgen Claesen3

  • 1Data Science Institute, Hasselt University, Belgium; Open Analytics NV, Antwerp, Belgium.

Computational biology and chemistry
|May 23, 2024
PubMed
概括

这项研究引入了一种新的变系数模型,用于在DNA甲基化数据中识别差异甲基化区域 (DMR). 该模型有效地处理杂的,稀疏的数据,并考虑过度分散,以有限的复制品改进DMR检测.

关键词:
贝塔-双项模型的模型.在CpG网站上.不同甲基化地区的区别.甲基化序列的排列方式平的线条可以使线条平滑.变化系数模型的变化系数模型

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