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Updated: Jun 25, 2025

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作为具有双重目标机制的抗癌剂的新型碳醇硫胺衍生物的结构-活性关系研究

Yonghua Liu1, Junyi Zhang1, Jiaqi Tian1

  • 1Institute of Medicinal Biotechnology, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, China.

European journal of medicinal chemistry
|May 23, 2024
PubMed
概括

新型碳醇硫胺体现出强烈的抗癌活性,通过抑制氨酸聚合并诱导亡. 这些化合物,特别是7和15,在临床前模型中表现出显著的疗效,为癌症治疗提供了一个有前途的新途径.

关键词:
反扩散活动的反扩散活动.这是一种抗瘤药物.碳醇硫胺的使用方法科尔奇辛的结合部位在这里,我们还可以看到Topo I.

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