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基于证据的关于胎儿疼痛和压力的讨论

Samirah H M Mohamed^1,2,3, Nadja Reissland⁴, Kanwaljeet J S Anand⁵

¹Obstetric Clinic at the Clinics Hospital of the Medical School, The University of São Paulo, São Paulo, Brazil.

|May 23, 2024

概括

胎儿疼痛是一个复杂的问题,但有证据表明,胎儿在没有麻醉的过程中可能会感到疼痛. 这项研究支持对所有胎儿使用麻醉,以尽量减少潜在的疼痛和压力反应.

科学领域:

围产儿医学围产儿医学
神经科学是一个神经科学.
胎儿生理学胎儿生理学

背景情况:

胎儿疼痛是在未经麻醉对早产新生儿和胎儿进行的程序中考虑的.
有证据表明,胎儿可能会在怀孕中期左右处理感知刺激.
胎儿疼痛的定义和经验仍在争论中,特别是关于国际疼痛研究协会 (IASP) 的定义.

研究的目的:

检查人类胎儿不能感受到疼痛的说法.
审查关于胎儿疼痛及其影响的科学证据.
论证受入侵手术的胎儿的生理和行为反应表明疼痛.

主要方法:

对胎儿和早产新生儿疼痛的临床研究的综述.
分析与胎儿视觉相关的解剖学和生理学数据.
对胎儿的压力激素,代谢变化,行为,血液动力学和面部表情的评估.

主要成果:

在侵袭性手术期间,在胎儿身上观察到压力激素,代谢变化,身体运动,血液动力学变化和与疼痛相关的面部表情的一致模式.
目前的证据并不能明确地驳斥过活力年龄的胎儿疼痛.
需要主观经验的IASP疼痛定义可能不完全适用于胎儿.

结论:

该研究建议,所有胎儿在侵袭性手术期间都应接受麻醉.
麻醉的目的是尽量减少胎儿的疼痛和生理应激反应.
这种方法旨在避免对母亲和婴儿造成不必要的并发症.

关键词:

胎儿麻醉胎儿麻醉胎儿的疼痛胎儿的疼痛胎儿的压力胎儿的压力胎儿外科手术胎儿外科手术婴儿-新生儿新生儿婴儿-早产的婴儿

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