相关实验视频

Updated: Jun 25, 2025

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms
09:51

Enhanced Genome Editing with Cas9 Ribonucleoprotein in Diverse Cells and Organisms

Published on: May 25, 2018

33.9K

通过CRISPR-Cas9加速基因组编辑

Amy R Eggers1, Kai Chen1, Katarzyna M Soczek2

  • 1Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA 94720, USA; Innovative Genomics Institute, University of California, Berkeley, Berkeley, CA 94720, USA.

Cell
|May 23, 2024
PubMed
概括

工程化Geobacillus stearothermophilus Cas9 (GeoCas9) 在其形域中的突变显著提高了人类细胞中的基因组编辑. 这种改进源于加速DNA解,为改进CRISPR-Cas9技术提供了新的策略.

关键词:
在CRISPR-Cas中在Cas9工程DNA 解在 GeoCas9在 R 循环中WED域名化电磁场基因组编辑在 iGeoCas9的使用

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