缺乏与患有炎症性肠病的患者的营养不良风险有关
Zihan Yu1, Wenxuan Song1, Xiangfeng Ren1
1Department of Gastroenterology and Hepatology, Tianjin Medical University General Hospital, Tianjin, China.
Postgraduate medicine
|May 23, 2024
概括
缺乏与炎症性肠病 (IBD) 患者营养不良的风险更高有关. 较低的血清水平独立地预测了这一群体的营养不良.
科学领域:
- 营养生物化学 营养生物化学
- 胃肠病学 胃肠病学
- 临床营养学 临床营养学
背景情况:
- 炎症性肠病 (IBD) 经常与营养不良有关,包括肉症和微量营养素缺乏.
- 微量元素,如 (Ca),对于评估营养状况至关重要,在营养不良中缺乏是常见的.
- 关于IBD患者营养不良和缺乏之间的具体联系的研究有限.
研究的目的:
- 调查诊断为炎症性肠病的患者中水平和营养不良之间的关联.
- 确定缺乏是否是IBD队列中营养不良的独立风险因素.
主要方法:
- 预期从149名IBD患者收集血液样本.
- 诱导合等离子体质谱法用于测量血清微量元素度.
- 后勤回归和接收器操作特征 (ROC) 曲线分析,以评估和营养不良之间的关系.
主要成果:
- 与非营养不良组相比,营养不良组的血清度明显较低 (87.03比89.36毫克/升,p=0.023).
- 血清水平低于87.21毫克/升被确定为营养不良的最佳预测指标 (ROC曲线下的面积=0.624,p=0.023).
- 在多变量分析中,水平<87.21 mg/L (OR=3.393) 和年龄独立与营养不良风险相关.
结论:
- 缺乏是患有炎症性肠病的患者营养不良的独立危险因素.
- 血清含量低于87.21毫克/升,表明IBD患者营养不良的风险明显更高.
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