东河 (日本) 的人类制造的加多:更新显示,从1996年到2020年,加多增加了7.7倍
Soma Kumasaka1,2, A Adhipatria P Kartamihardja3,4, Yuka Kumasaka3
1Department of Diagnostic Radiology and Nuclear Medicine, Gunma University Graduate School of Medicine, 3-39-22 Showa-machi, Maebashi, Gunma, 371-8511, Japan. kumasaka88@gunma-u.ac.jp.
European radiology experimental
|May 23, 2024
概括
来自医疗对比剂的人类制造的加多 (Gd) 在日本的河显著增加,在24年内增加了7.7倍. 这一增长与医院数量和MRI使用量相关,突出显示了环境问题.
科学领域:
- 环境化学环境化学
- 环境科学 环境科学
- 毒理学 毒理学 毒理学
背景情况:
- 在MRI中使用的基于Gd的对比剂 (GBCA) 的人类制造的加多 (Gd) 在水生环境中很普遍.
- 有关人为Gd.的毒性和生物积累存在担忧.
- 本研究调查了日本东河的Gd水平,将当前数据与1996年的数据进行比较.
研究的目的:
- 量化Tone河的人为Gd度.
- 评估Gd异常和医疗保健基础设施之间的相关性.
- 将当前的Gd水平与1996年的历史数据进行比较.
主要方法:
- 2020年8月,在Tone河15个地点收集的水样.
- 使用感应合等离子体质谱分析的稀土元素 (REEs).
- 计算并与医院数量和MRI单位相关联的Gd异常.
主要成果:
- 所有样本都显示出正的Gd异常,范围为121%至6.545%.
- 沿河的Gd异常呈现下降和增加的趋势.
- 在Gd异常与医院数量 (r=0.88) 和MRI单位数量 (r=0.89) 之间发现了强烈的正相关性.
结论:
- 在Tone河中检测到显著的人为Gd异常.
- 与1996年的水平相比,Gd异常增加了7.7倍,表明GBCA使用量增加.
- 对人为Gd的健康风险和去除技术进行进一步的研究是有必要的.
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