互感训练会影响前半岛皮层的神经回路
Ayako Sugawara1, Ruri Katsunuma1,2, Yuri Terasawa1,3
1Department of Behavioral Medicine, National Institute of Mental Health, National Center of Neurology and Psychiatry, Tokyo, Japan.
Translational psychiatry
|May 23, 2024
概括
互感训练提高了感知身体内部信号的准确性,减少了焦虑和身体症状. 这与大脑连接的变化有关,特别是涉及前半岛皮层.
科学领域:
- 神经科学是一个神经科学.
- 心理生理学 心理生理学
- 认知科学 认知科学
背景情况:
- 内感,即对身体内部信号的感知,对于恒温和情绪调节至关重要.
- 以前的研究表明,通过认知训练可以提高整感知精度.
- 前半岛皮层 (AIC) 是整感觉的关键大脑区域.
研究的目的:
- 来自AIC的研究整体感应训练对静止状态功能连接 (RSFC) 的影响.
- 探索神经机制,以改善整体感知准确性和减少焦虑和体质症状.
主要方法:
- 一个纵向干预研究,涉及整感受训练.
- 功能磁共振成像 (fMRI) 测量RSFC在训练前和训练后.
- 一个心跳感知任务来评估整感知准确性.
主要成果:
- 互感训练提高了互感准确性,减少了焦虑,并减轻了身体症状.
- 从AIC增加的RSFC到背侧前额叶皮层 (DLPFC),上边缘 (SMG),前带皮层 (ACC) 和大脑干 (包括单独核通道,NTS).
- 从AIC到视觉皮层 (VC) 的RSFC降低与改善的整感准确性相关.
结论:
- 互感培训调节了AIC连接,影响了自下而上的 (AIC-ACC-NTS) 和自上而下的 (AIC-DLPFC-SMG) 互感过程.
- 这些神经变化提供了一个机械的理解,如何整体感应训练减轻体质症状和焦虑.
- 这些发现支持开发针对精神病状况神经基础的新型心理治疗方法.
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