在急性缺血性中风中病变分布的季节性变化:一项回顾性研究
Xiao Sun1, Xiaoshuang Xia1, Juanjuan Xue1
1Department of Neurology, The Second Hospital of Tianjin Medical University, Tianjin, China.
Scientific reports
|May 23, 2024
概括
冬季与急性缺血性中风 (AIS) 中多重和双边病变的风险更高有关. 这种季节性模式在大动脉动脉样硬化和小动脉阻塞中风亚型中尤为明显.
科学领域:
- 神经学 神经学
- 流行病学 流行病学
- 医疗成像医学成像
背景情况:
- 季节性变化影响疾病发生率和结果.
- 季节性变化与急性脑梗塞位置之间的关系尚不清楚.
- 了解这些模式对于公共卫生战略至关重要.
研究的目的:
- 调查急性缺血性中风 (AIS) 病变发病季节和病变分布之间的关联.
- 识别特定的中风亚型,这些中风亚型在病变模式中表现出显著的季节性变化.
主要方法:
- 从2018-2022年对1488名AIS患者的回顾性分析.
- 患者按发病季节 (春季,夏季,秋季,冬季) 分类.
- 通过MRI评估的损伤分布,包括前/后/双循环心脏病发作 (DCI),单侧/双侧以及单/多次心脏病发作.
- 用于确定季节性关联的物流回归模型,并对中风亚型进行子组分析.
主要成果:
- 与夏季相比,冬季发作与多发性心脏病发作 (2.15倍),双边心脏病发作 (2.69倍) 和DCI (1.54倍) 的风险明显增加.
- 小动脉封闭 (SAO) 和大动脉动脉样硬化 (LAA) 亚型在冬季显示多发或双边心脏病发作和DCI的风险增加.
- 对于心血管栓塞性中风亚型,没有发现显著的季节性关联.
结论:
- 在AIS的病变分布中存在显著的季节性变异,特别影响LAA和SAO亚型.
- 冬季的开始为AIS中的特定病变模式带来了独特的风险概况.
- 这些发现可以为开发适合不同中风亚型的气象风险预警系统提供信息.
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