大脑不对称性的临床影响
Sebastian Ocklenburg1,2,3, Annakarina Mundorf4,5, Robin Gerrits6,7
1Department of Psychology, MSH Medical School Hamburg, Hamburg, Germany. sebastian.ocklenburg@medicalschool-hamburg.de.
Nature reviews. Neurology
|May 23, 2024
概括
个人的大脑不对称性有很大差异,影响神经疾病. 虽然不是诊断,但这些变异提供了对临床神经病学的症状发作和治疗反应的见解.
科学领域:
- 神经科学是一个神经科学.
- 神经学 神经学
- 人类解剖学 人类解剖学
背景情况:
- 每个人的大脑都有独特的结构和功能特征.
- 大脑不对称,无论是功能还是结构,都是一个核心的组织原则.
- 大脑不对称的个体变异性越来越被认为是临床相关的.
研究的目的:
- 审查当前对大脑不对称性的理解.
- 探索大脑不对称的变化及其临床意义.
- 讨论大脑不对称性在各种神经和精神疾病中的相关性.
主要方法:
- 对最近关于大脑不对称性的发现进行了全面的审查.
- 重点是大规模的数据库研究和元分析.
- 在神经精神病,神经发育和学习障碍的背景下检查大脑不对称性.
主要成果:
- 大脑不对称性存在显著的个体变异性.
- 大脑不对称的变化与神经退行性疾病的症状发作有关.
- 大脑不对称性对横向治疗有影响,例如大脑刺激.
结论:
- 大脑不对称的变化对于诊断生物标志物来说还不够具体.
- 大脑不对称性可以作为症状或治疗反应在特定的神经学环境中的生物标志物.
- 提供了关于将大脑不对称性的见解纳入临床神经学实践的建议.
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