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Updated: Jun 25, 2025

Assessment of Mitochondrial Functions and Cell Viability in Renal Cells Overexpressing Protein Kinase C Isozymes
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Published on: January 7, 2013

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葡萄糖生成酶PCK2在内皮细胞的蛋白质稳定中具有非酶作用

Pauline de Zeeuw1,2,3, Lucas Treps1,2,4, Melissa García-Caballero1,2,5

  • 1Laboratory of Angiogenesis and Vascular Metabolism, Department of Oncology, KU Leuven, Leuven, B-3000, Belgium.

Communications biology
|May 23, 2024
PubMed
概括

当葡萄糖稀缺时,内皮细胞 (ECs) 使用涉及PCK2的截断葡萄糖生成 (GNG) 途径. 这一途径支持生物合成,并意外地保持了蛋白质的稳定性,这对于EC生存和血管形成至关重要.

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