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激活Nrf2/HO-1信号通路会加剧胆固醇性肝损伤

Yi Wang1,2, Xiaolong Fu1,2, Li Zeng1,2

  • 1Key Laboratory of Basic Pharmacology of Ministry of Education and Joint International Research Laboratory of Ethnomedicine of Ministry of Education, Zunyi Medical University, Zunyi, China.

Communications biology
|May 23, 2024
PubMed
概括

核因素红色素2相关因子-2 (Nrf2) 和血红氧酶-1 (HO-1) 的激活通过增加胆红素来加剧胆固醇性肝损伤. 抑制HO-1或改善胆红素运输可以保护肝脏免受损伤.

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