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夜和阻塞性睡眠呼吸暂停症

Olaf P J Vrooman¹, Philip E V van Kerrebroeck², Michael R van Balken³

¹Department of Urology, Hospital Rijnstate Arnhem, Arnhem, Netherlands. o.vrooman@gmail.com.

Nature reviews. Urology

|May 23, 2024

概括

夜尿或夜间排尿在阻塞性睡眠呼吸暂停 (OSA) 中很常见. 虽然持续的正气道压力有助于一些患者,但将OSA和夜联系在一起的复杂机制需要进一步的研究和多学科的方法.

科学领域:

泌尿器科泌尿器科泌尿器科泌尿器科
睡眠医学睡眠医学
心脏病学心脏病学

背景情况:

夜是被诊断患有阻塞性睡眠呼吸暂停 (OSA) 的患者的常见投诉.
持续的正气道压力 (CPAP) 疗法显示出缓解夜的潜力,但其精确的机制仍未完全阐明.
现有的理论,如心脏过载-自然路径,在完全解释与OSA相关的夜方面存在局限性.

研究的目的:

探索阻塞性睡眠呼吸暂停和夜之间的复杂关系.
讨论解释OSA患者夜的当前理论的局限性.
在OSA的背景下,倡导一个全面的,多学科的夜病管理策略.

主要方法:

文献综述和现有关于OSA和夜的研究的综合.
分析受OSA影响的生理途径,包括自主功能障碍,氧化应激和内皮损伤.
考虑导致夜尿症的多因素因素,如并发症,药物和生活方式.

主要成果:

阻塞性睡眠呼吸暂停显著影响涉及尿道调节的生理系统.
将OSA与夜尿症联系在一起的病理生理学是复杂的,不仅涉及常见的尿性反应.
有效的夜尿病管理需要整体地解决OSA和相关因素.

结论:

整合睡眠医学,泌尿病学和生活方式改变的综合方法对于在OSA患者中管理夜是必不可少的.
泌尿科医生必须认识到OSA的生理影响,并为患有夜尿症的患者提供睡眠评估.
替代治疗方法,如口腔器械和手术,可以补充CPAP治疗选择的个人.

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