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Updated: Jun 25, 2025

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
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naRNA-LL37复合DAMP将无菌NET定义为炎症的自我传播驱动因素

Francesca Bork1, Carsten L Greve1, Christine Youn2

  • 1Institute of Immunology, Department of Innate Immunity, University of Tübingen, Auf der Morgenstelle 15, 72076, Tübingen, Germany.

EMBO reports
|May 23, 2024
PubMed
概括

与NET相关的RNA (naRNA) 通过刺激进一步的NET形成来放大中性粒细胞激活和皮肤炎症. 这一途径涉及TLR8-NLRP3炎症酶和NOD2信号传递,为牛皮等炎症性疾病提供了潜在的治疗点.

关键词:
垃圾填埋场是一个垃圾填埋场.在 NLRP3 炎症酶体中,NLRP3 炎症酶体是中性细胞外细胞陷这是一个RNARNARNARNARNA.类似于收费的受体.

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