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患有周围胆管癌和以前胆管仪器的患者的结局:一项观察性研究

Karen T Brown^1,2, Joanne F Chou³, Hannah B Suchy^4,5

¹Department of Radiology, New York-Presbyterian Hospital, New York, NY, USA. sxa9001@med.cornell.edu.

BMC gastroenterology

|May 23, 2024

概括

对周围胆管癌的跨毛囊胆管排水增加了胆管炎的风险,延迟了治疗,减少了生存率. 在干预之前寻求专家评估,以避免并发症.

科学领域:

肝胆道手术肝胆道手术
胃肠病学胃肠病学
在瘤学瘤学.

背景情况:

周围胆管癌 (PHC) 是一种具有挑战性的上胆道癌.
对PHC患者的最佳管理策略进行了讨论,这些患者有或没有先前胆道排水.

研究的目的:

评估患有周围胆管癌的患者的结局.
评估先前存在的跨乳头胆道排水对患者结局的影响.

主要方法:

一个回顾性审查的106名患者与PHC诊断在2013-2017年期间.
对临床数据和成像研究的分析,以比较先前有胆汁排水和没有胆汁排水的患者之间的结果.

主要成果:

69%的患者在呈现之前经历过过毛囊胆道排水.
之前排水的患者患上胆管炎的发病率明显较高 (18%对0%,p=0.008).
胆管炎导致治疗延迟和中位数整体存活时间较差 (13.6个月对20.6个月,p=0.043).

结论:

对于PHC而言,跨乳头胆道排水与胆管炎的风险,治疗延迟和生存率降低有关.
在任何干预之前,在专门的癌症中心进行早期评估至关重要.
避免不必要的胆道排水可以改善治疗时间表和患者的结果.

关键词:

胆道癌症是胆道的癌症.胆管支架是一种胆管支架.内镜式支架 (endoscopic stent) 是一种内镜式支架.周部状胆管癌 (Peri-hilar cholangiocarcinoma) 是一种发生在周部状胆管癌的疾病.

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