研究方案:针对双相情感障碍患者亲属的基于小组的精神教育 - - 一个大规模的现实世界随机对照并行小组试验,R-双相RCT
Julie Ravneberg Stokholm1,2, Maj Vinberg3,4, Maria Faurholt-Jepsen5,3
1Psychiatric Center Copenhagen, The Copenhagen Affective Disorder Research Center (CADIC), Copenhagen, Denmark. julie.ravneberg.stokholm@regionh.dk.
Trials
|May 23, 2024
概括
对双相情感障碍 (BD) 患者的亲属进行小组精神教育,可以减少情绪不稳定. 这项大规模的试验调查了其现实世界的有效性,测量了亲属和患者的结果.
科学领域:
- 精神病学是一个精神病学.
- 临床心理学 临床心理学
- 公共卫生 公共卫生
背景情况:
- 双相情感障碍 (BD) 患者的亲属经历了显著的情绪负担,压力和抑郁症状.
- 这种负担可能会加剧患者的不稳定,并增加复发率.
- 在BD患者亲属的现实环境中,以小组为基础的精神教育的有效性仍未得到充分研究.
研究的目的:
- 为了评估基于BD患者的亲属群体精神教育的有效性.
- 评估这种干预对亲属情绪不稳定和其他情感症状的影响.
- 确定患者和亲属的情绪不稳定和情感症状是否有所不同.
主要方法:
- 一个大规模的,现实世界的,双臂,平行组随机对照试验 (RCT).
- 200名亲属按1比1随机分配到小组精神教育或等候名单 (4个月),随后接受精神教育.
- 主要结果:通过每天的智能手机自我评估,情绪不稳定;次要结果包括患者报告的负担,自我有效性和BD知识.
主要成果:
- 这项研究正在进行中,结果尚未公布.
- 这项试验是第一个使用亲属情绪不稳定作为主要结局的大规模RCT.
- 它也是第一个研究患者及其亲属之间情感症状的共变性的研究.
结论:
- 本协议概述了一种新的,可行的群体心理教育干预措施,用于BD患者的亲属.
- 该干预旨在适用于现实世界的精神病学环境,资源有限.
- 调查结果将为受双相情绪障碍影响的家庭实施支持性干预提供信息.
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