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认知融合的价值针对性和标准的系统性横直肠前列腺活检用于前列腺癌诊断
Lu-Ping Yu1, Yi-Qing Du, Yi-Ran Sun
1Department of Urology, Peking University People's Hospital, Beijing 100044, China.
Asian journal of andrology
|May 24, 2024
概括
将向活检 (TB) 与系统活检 (SB) 结合起来,可以提高前列腺癌 (PCa) 检测准确度. 对于单边病变,TB加上ipsilateral SB为PCa和临床显著PCa (csPCa) 提供了高的检测率.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 放射学 放射学是一门学科.
- 在瘤学瘤学.
背景情况:
- 磁共振成像 (MRI) 有助于检测前列腺癌 (PCa) 病变.
- 准确诊断PCa和临床显著PCa (csPCa) 对于有效治疗至关重要.
- 有不同的活检策略,包括系统活检 (SB) 和向活检 (TB).
研究的目的:
- 为了比较认知融合引导的向活检 (TB),系统活检 (SB) 和结合TB+SB用于PCa和csPCa检测的诊断准确度.
- 评估单边MRI病变患者中各种活检组合的检测率.
主要方法:
- 对180名患有结核病和SB的前列腺活检的患者进行了回顾性分析.
- 使用McNemar测试检测PCa和csPCa检测率的比较.
- 在单边病变病例中对TB,SB,TB+ipsilateral-SB (ipsi-SB),TB+contralateral-SB (contra-SB) 和TB+SB进行评估.
主要成果:
- 结核病+SB组合的PCa检测率 (66.7%) 比单独结核病 (52.8%) 或SB (62.2%) 的检测率更高.
- 与结核病 (46.1%) 或SB (56.7%) 相比,结核病+SB组合也产生了较高的csPCa检测率 (58.3%).
- 对于单侧病变,TB+ipsi-SB检测到96.4%的PCa和95.9%的csPCa病例.
结论:
- 与单独使用任何一种方法相比,结核病+SB的组合为前列腺癌提供了更高的诊断准确性.
- 结核病+ipsi-SB是一种潜在的合适策略,适用于MRI检测到单边前列腺病变的患者.
- 优化的活检方案提高了临床上显著的前列腺癌的检测.
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