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Updated: Jun 25, 2025

A Scalable Balz-Schiemann Reaction Protocol in a Continuous Flow Reactor
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在连续流中对N-Boc受保护氨基进行选择性热去保护

Michelle-Rose Ryan1, Denis Lynch1, Stuart G Collins2

  • 1School of Chemistry, Analytical and Biological Chemistry Research Facility, University College Cork, Cork T12 YN60, Ireland.

Organic process research & development
|May 24, 2024
PubMed
概括

这项研究证明了在连续流中氨基的高效,无催化剂的热N-Boc降解保护. 通过温度控制实现了选择性降低保护,使不同N-Boc组的顺序去除成为可能.

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