在Masimo O3近红外光谱测量中缓慢波的传输
Claudia A Smith1,2, Agnieszka Kazimierska3, Michał M Placek2
1Division of Neurosurgery, Department of Clinical Neurosciences, University of Cambridge, Cambridge, UK.
近红外光谱 (NIRS) 可以在血压变化期间检测大脑自调节 (CA) 缓慢波. 马西莫O3指标显示CA评估有前途,但需要对脑损伤患者进行进一步研究.
科学领域:
- 神经科学是一个神经科学.
- 生物医学工程 生物医学工程
背景情况:
- 大脑自调节 (CA) 功能障碍是脑损伤后的重要并发症.
- 近红外光谱 (NIRS) 提供了一种潜在的非侵入性CA评估方法,可以替代跨的多普勒脑血流速度 (CBFV) 测量.
研究的目的:
- 为了确定在自发和诱导的动脉血压 (ABP) 变化期间是否可以使用Masimo O3 NIRS参数检测健康志愿者的自我调节缓慢波 (0.005-0.05 Hz).
- 为了比较NIRS衍生的慢波传输与CBFV.
主要方法:
- 10名健康志愿者在基线和坐/站动作期间测量了ABP,CBFV和Masimo O3参数,以诱导ABP振荡.
- 使用功率光谱密度和连贯性分析来评估NIRS信号中的慢波传输,并将其与CBFV进行比较.
主要成果:
- 在基线大多数参数中检测到缓慢波,除了脑氧和.
- 在诱导的ABP振荡 (0.033赫兹) 期间,慢波功率在所有参数中都同样增加.
- 来自NIRS的总 (cHb) 和氧化 (O2Hb) 血红蛋白度与CBFV的度非常相似.
- 在诱导变化期间,CBFV和NIRS测量对ABP的一致性显著增加.
结论:
- 在某种程度上,Masimo O3 NIRS指标可以检测出ABP的自发波动.
- 需要进行进一步的研究,以确定Masimo O3信号对脑损伤患者的CA评估的临床实用性.
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