实际临床实践评估:用于评估认知衰退相当于痴呆症的快速和易于使用的工具
Takayuki Asano1, Asako Yasuda1, Setsuo Kinoshita1
1Research and Development, Nippontect Systems Company Limited, Tokyo, JPN.
Cureus
|May 24, 2024
概括
该ONSEI工具使用20秒的智能手机分析准确地选出暗示痴呆症的认知衰退. 这种快速查有助于早期检测,并促进风险较高的人更好地自我照顾.
科学领域:
- 神经学 神经学
- 老年学是一门学科.
- 医疗保健中的人工智能
背景情况:
- 认知衰退查对于早期干预和未来规划至关重要.
- 现有的选方法可能缺乏速度和可访问性.
- ONSEI工具是为了解决这些局限性而开发的.
研究的目的:
- 评估ONSEI工具在识别认知衰退等同于痴呆症时的准确性.
- 评估ONSEI在现实世界临床环境中的表现.
主要方法:
- 追溯观察性研究,涉及来自日本神经外科诊所的参与者.
- 利用机器学习算法分析来自口语响应的年龄,时间导向任务得分和声学特征.
- 通过智能手机或平板电脑进行的ONSEI分析.
主要成果:
- 实现了98.1% (p<0.001) 的高整体分类准确度.
- 显示出出色的敏感性 (97.3%,p<0.001) 和特异性 (98.5%,p<0.001).
- 在各种年龄组中观察到一致的准确性.
结论:
- 在认知上正常的个体中,ONSEI工具对痴呆症查具有很高的诊断准确性.
- 它的有效性独立于临床设施或参与者的年龄.
- ONSEI是用于痴呆症查和促进自我护理的宝贵工具.
更多相关视频
06:23The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
Published on: October 13, 2016
32.3K
08:07Traditional Trail Making Test Modified into Brand-new Assessment Tools: Digital and Walking Trail Making Test
Published on: November 23, 2019
11.1K
相关概念视频
Dementia
111
Dementia is a collective term for cognitive disorders primarily affecting memory, thinking, and reasoning. It is not a specific disease but a syndrome, with Alzheimer's disease being the most common cause, accounting for approximately 60-80% of cases. Other types include vascular dementia, Lewy body dementia, and frontotemporal dementia. Dementia affects millions worldwide, particularly older adults, though it is not a normal part of aging.
The progression of dementia is generally gradual....
The progression of dementia is generally gradual....
111
Cognitive Development During Adulthood
93
Cognitive development continues throughout adulthood, undergoing significant shifts across early, middle, and late stages. Individual transition occurs from adolescent idealism to pragmatic and adaptable thinking in early adulthood. During this period, individuals learn to integrate personal beliefs with the recognition that other perspectives are equally valid. Exposure to the complexities of modern society, diverse experiences, and higher education contribute to this adaptive thought process,...
93
Alzheimer's Disease: Overview
465
Alzheimer's Disease (AD) is a continually advancing neurodegenerative disorder, distinguished by escalating memory loss, cognitive dysfunction, and dementia. The disease unfolds in three stages: preclinical, mild cognitive impairment (MCI), and dementia. Its onset is insidious, and the progression gradual, with the cause not well explained by other disorders.
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
The clinical diagnosis of AD hinges on the presence of memory and other cognitive impairments. Biomarkers, such as changes in Aβ...
465
Cognitive Enhancers: Cholinesterase Inhibitors and NMDA Receptor Antagonists
120
Cognitive enhancers, also known as "smart drugs," are substances used to enhance memory, mental alertness, and concentration. These can be natural or synthetic and improve cognition in conditions like Alzheimer's disease (AD) and other neurodegenerative diseases. Some common examples include caffeine, amphetamines, methylphenidate, modafinil, arecoline, donepezil, vortioxetine, and piracetam. These enhancers work on the principle of synaptic plasticity and altered circuit function.
120
