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Updated: Jun 25, 2025

Methods for the Discovery of Novel Compounds Modulating a Gamma-Aminobutyric Acid Receptor Type A Neurotransmission
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卡尔顿因衍生化合物用于向性胆酶抑制的向性胆酶抑制

Filip Pidany1, Jana Kroustkova1, Jaroslav Jenco1

  • 1Faculty of Pharmacy in Hradec Kralove, Department of Pharmacognosy and Pharmaceutical Botany, Charles University Akademika Heyrovskeho 1203 500 05 Hradec Kralove Czech Republic cahlikova@faf.cuni.cz.

RSC medicinal chemistry
|May 24, 2024
PubMed
概括

新型阿尔茨海默氏病 (AD) 药物候选物向人类胆固醇化酶 (hBChE) 的药物是从Amaryllidaceae的化物开发出来的. 化合物28和33显示强大的hBChE抑制和有利的类似药物的AD治疗属性.

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