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Updated: Jun 25, 2025

System for Efficacy and Cytotoxicity Screening of Inhibitors Targeting Intracellular Mycobacterium tuberculosis
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针对Mycobacterium tuberculosisII型NADH脱酶的2-mercaptobenzothiazole衍生物的抗结核活性是针对的

Pallavi Saha1, Shashikanta Sau2, Nitin Pal Kalia2

  • 1Department of Pharmaceutical Engg. and Tech, IIT-Banaras Hindu University Varanasi UP 221005 India deepak.phe@itbhu.ac.in.

RSC medicinal chemistry
|May 24, 2024
PubMed
概括

研究人员开发了新型的2-mercaptobenzothiazole化合物,作为Mycobacterium结核病II型NADH脱酶 (NDH-2) 的潜在抑制剂. 化合物C3,C4和C11表现出显著的抗结核活性和NDH-2抑制,具有良好的安全性.

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