我们在患有状细胞贫血的儿童中缺少甲状腺功能低下吗?
S O Akodu1, A F Adekanmbi1, T A Ogunlesi1
1Department of Paediatrics, Olabisi Onabanjo University Teaching Hospital, Sagamu, Ogun, Nigeria.
Ethiopian journal of health sciences
|May 24, 2024
概括
亚临床甲状腺功能低下症影响尼日利亚儿童患有状细胞贫血. 建议对这些患者进行常规甲状腺查,以确保早期检测和治疗甲状腺功能障碍.
科学领域:
- 儿科内分泌学 儿科内分泌学
- 血液学 血液学 血液学
- 代谢障碍 代谢障碍 代谢障碍
背景情况:
- 状细胞贫血 (SCA) 患者因慢性输血和潜在的甲状腺缺血而面临甲状腺功能低下的风险.
- 有限的研究存在于尼日利亚儿童SCA的甲状腺功能低下的患病率.
研究的目的:
- 为了确定尼日利亚儿童诊断出状细胞贫血的甲状腺功能低下的患病率.
主要方法:
- 一项涉及Olabisi Onabanjo大学教学医院 (Sagamu) 71名SCA儿童的横截面研究.
- 测试了血清甲状腺激素 (自由T3,自由T4) 和甲状腺刺激激素 (TSH).
- 根据适合年龄的参考值对甲状腺功能低下症进行分类 (亚临床,初级,二级).
主要成果:
- 整体患病率:原发性甲状腺功能低下率为0%,次发性甲状腺功能低下率为0%,亚临床甲状腺功能低下率为4.2%.
- 7.0%的受试者患有提升的TSH;1.4%患有低自由T3;11.3%患有低自由T4.
- 不同年龄组的激素水平是可比的.
结论:
- 在尼日利亚患有状细胞贫血的儿童中存在亚临床甲状腺功能低下症.
- 建议对所有患有SCA的儿童进行常规的甲状腺功能低下症查.
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