对患有炎症性肠道疾病的人进行接受和承诺治疗和基于同情心的小组干预的随机对照试验:LIFEwithIBD干预
Cláudia Ferreira1, Joana Pereira1, David Skvarc2
1CINEICC, Faculty of Psychology and Education Sciences, University of Coimbra, Coimbra, Portugal.
Frontiers in psychology
|May 24, 2024
概括
这项研究评估了针对炎症性肠病 (IBD) 患者的LIFEwithIBD干预方案. 该疗法在减少焦虑和疾病严重程度方面显示了初步好处,尽管在所有结果中并不一致.
科学领域:
- 胃肠病学 胃肠病学
- 心理学 心理学 心理学
- 临床试验 临床试验
背景情况:
- 炎症性肠病 (IBD) 显著影响患者的生活质量,经常与心理困扰同时发生.
- 接受和承诺疗法 (ACT) 和基于同情心的干预措施显示了治疗慢性疾病的潜力.
研究的目的:
- 评估LIFEwithIBD干预措施的可接受性和有效性,结合ACT和以同情心为中心的治疗,在IBD患者中.
- 评估干预对心理症状和疾病活动的影响.
主要方法:
- 一个双臂随机对照试验 (RCT) 涉及54名IBD患者 (25项干预,29名等候名单控制).
- 在12个月内进行的干预,在基线,干预后和3个月和12个月后续的评估.
- 主要结局包括抑郁,焦虑和压力症状;次要结局包括疾病生物标志物.
主要成果:
- 参与者对LIFEwithIBD干预非常满意.
- 两组都在压力和IBD症状感知方面表现出初步改善.
- 干预组在3个月后报告克罗恩病症状严重程度明显降低,焦虑症状显著减少.
结论:
- LIFEwithIBD干预表明有希望的,尽管是初步的,对管理IBD疾病活动和严重心理痛苦的患者的焦虑有好处.
- 需要进一步的研究来证实这些发现,并探索长期影响.
相关概念视频
Inflammatory Bowel Disease III: Diagnostic Studies and Management I-Nutritional Therapy
331
Various diagnostic tests are employed in the diagnostic process for Inflammatory Bowel Disease (IBD), particularly to differentiate between Crohn's disease and ulcerative colitis.
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
Diagnostic studies
A colonoscopy is the definitive screening test, distinguishing ulcerative colitis from other colon diseases with similar symptoms. During a colonoscopy test, inflamed mucosa with exudate ulcerations can be observed, and biopsies are taken to determine the histologic characteristics of the...
331
Inflammatory Bowel Disease II: Crohn's Disease
217
Introduction
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
Inflammatory bowel disease, commonly known as IBD, refers to a collection of disorders that lead to persistent inflammation of the gastrointestinal tract. The two types of IBD are ulcerative colitis, which impacts the colon, and Crohn's disease, which can involve any part of the gastrointestinal segment.
Crohn's disease
Crohn's disease is a chronic, systemic inflammatory bowel disease (IBD) that predominantly affects the gastrointestinal tract. It is marked by...
217
Inflammatory Bowel Disease V: Surgical Management
144
Surgical interventions for inflammatory bowel disease (IBD), which includes ulcerative colitis and Crohn's disease, are essential in managing symptoms and addressing complications. The selection of surgical procedures is contingent upon the specific conditions and complications that stem from these illnesses.
Here are some common surgical interventions for IBD:
Here are some common surgical interventions for IBD:
144
Inflammatory Bowel Disease IV: Pharmacological Management
126
Upon diagnosis, managing Inflammatory Bowel Disease (IBD) involves addressing several crucial aspects. The primary goals include resting the bowel, correcting malnutrition, and providing symptomatic relief. Resting the bowel may consist of medications to reduce inflammation and promote healing. Correcting malnutrition is essential, often requiring dietary adjustments and nutritional supplements. Symptomatic relief aims to ease pain, diarrhea, and other discomforts in IBD.
Pharmacologic...
Pharmacologic...
126
Inflammatory Bowel Disease I: Ulcerative Colitis
165
Introduction
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
Inflammatory bowel disease, or IBD, encompasses a group of disorders characterized by chronic inflammation or ulceration of the gastrointestinal tract.
Risk Factors
The exact cause of IBD remains unclear, although it is believed to be due to a mix of genetic, environmental, microbial, and immune factors. Genetic factors are significant in determining susceptibility to IBD, with family history being a critical risk factor. Individuals with a first-degree relative who has IBD are at...
165
Drugs for Treatment of Crohn's Disease in IBD Using Immunomodulatory Agents
158
Crohn's disease is an inflammatory bowel disorder marked by chronic inflammation of the GI tract. Various treatment strategies for Crohn's disease are employed, such as immunomodulatory agents, glucocorticoids, and biologics or anti-TNF therapy. Azathioprine (Imuran), a commonly used immunomodulatory drug for Crohn's disease, is converted in the body to mercaptopurine, which inhibits purine biosynthesis and cell proliferation. Both are utilized in severe cases of Inflammatory Bowel...
158


