初级保健患者有兴趣参加计划中的多种癌症早期检测临床试验
Ronald E Myers1, Mie H Hallman1, Ayako Shimada2
1Division of Population Science, Department of Medical Oncology, Thomas Jefferson University, Philadelphia, Pennsylvania, USA.
Cancer medicine
|May 24, 2024
概括
在初级保健中招募多种癌症早期检测 (MCED) 测试是可行的. 大多数接触的患者表现出对MCED试验参与的兴趣和较低的决策冲突.
科学领域:
- 在瘤学瘤学.
- 预防医学 预防医学
- 临床试验 临床试验
背景情况:
- 多种癌症早期检测 (MCED) 测试正在出现用于癌症查.
- 评估MCED测试的安全性和有效性需要强大的临床试验.
- 正在调查在初级保健机构中招募患者参加MCED试验的可行性.
研究的目的:
- 评估招募初级保健患者参加多种癌症早期检测 (MCED) 临床试验的可行性.
- 评估患者参与MCED试验的兴趣.
- 测量考虑参加MCED试验的患者之间的决策冲突.
主要方法:
- 电子医疗记录确定了1000名符合条件的50-80岁初级保健患者.
- 患者收到邮件信息,并通过电话联系同意和调查.
- 采访和终点调查评估了对参与试验的看法,兴趣和决策冲突.
主要成果:
- 与690名 (69%) 确诊患者建立了联系.
- 217名患者 (31%) 完成了决策咨询,219名患者 (32%) 完成了终点调查.
- 在受访者中,81%的人对加入MCED试验感兴趣,74%的人表示决策冲突较低.
结论:
- 对于MCED试验的初级保健患者外展是可行的,观察到显著的兴趣和低的决策冲突.
- 需要进一步的研究来优化患者外展战略.
- 让患者参与共享决策对于成功参与MCED试验至关重要.
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