[COVID-19肺炎中肺部空心的危险因素]
Z G Berikkhanov1, S N Avdeev1, G V Neklyudova1
1Sechenov First Moscow State Medical University, Moscow, Russia.
Khirurgiia
|May 24, 2024
概括
在COVID-19肺炎中,肺部腔化与严重的肺损伤和缺乏生物治疗有关. 这种并发症并不典型,可能源于感染或心脏病发作,需要进一步研究.
科学领域:
- 肺部病理学 肺部病理学
- 传染性疾病 传染性疾病
- 放射学 放射学是一门学科.
背景情况:
- COVID-19肺炎可能导致各种并发症.
- 肺腔位是一种不常见但严重的表现.
- 识别风险因素对于患者管理至关重要.
研究的目的:
- 为了确定COVID-19肺炎中与肺部腔化相关的风险因素.
- 分析化发展的临床和放射学预测因素.
主要方法:
- 对8261名COVID-19患者 (2020年4月至2022年3月) 的回顾性研究.
- 40名患有肺腔异位的患者与40名没有肺腔异位的患者进行了比较,根据年龄,肺体积和氧化量进行了匹配.
- 评估临床数据,并发病症,治疗方法和CT成像发现.
主要成果:
- 肺腔化与年龄较大,氧和度较低 (SpO2),肺损伤体积较大,非侵入性通风和更长的住院时间有关.
- 多变量分析确定了基于CT的肺损伤严重程度和缺乏生物治疗 (IL-6抑制剂) 作为关键预测因素.
- 肺腔异位并没有显著影响该队列的死亡率.
结论:
- 先进的肺损伤和延迟/缺席的生物疗法是COVID-19肺部空心的重要危险因素.
- 其他可能的原因包括二次感染 (真菌,细菌),结核病和肺梗塞.
- 需要进一步的研究来确定这种并发症的诊断和治疗策略.
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