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与无症状左心室透静功能障碍的风险分析相关的因素在非透析患者中,这些患者患有慢性脏病
Yajuan Gao1, Shengnan Chen1, Jiani Fu1
1Department of Nephrology, The First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Renal failure
|May 24, 2024
概括
超过92%的慢性病 (CKD) 患者有无症状的左心室扩张功能障碍 (ALVDD). 年龄,糖尿病病,高血压,CKD阶段,血压,尿蛋白和低是ALVDD的关键危险因素.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學.
- 心脏病学 心脏病学
- 内部医学 内部医学
背景情况:
- 心力衰竭 (HF) 是慢性病 (CKD) 患者结果的重要预测因素.
- 左心室扩张功能障碍 (LVDD) 是常见的原因,在CKD中具有保留喷射分数 (HFpEF) 的HF.
- 识别LVDD的风险因素对于管理心血管疾病 (CVD) 在CKD中至关重要.
研究的目的:
- 为了确定无症状的左心室透静功能障碍 (ALVDD) 在非透析的CKD患者中的患病率.
- 在这个人群中确定与ALVDD相关的临床和人口因素.
主要方法:
- 追溯横截面研究,涉及339名非透析的慢性病患者.
- 收集临床和心声回声数据.
- 多变量逻辑回归分析以确定ALVDD的风险因素.
主要成果:
- 在研究队列中观察到ALVDD的高患病率 (92.04%).
- 与ALVDD风险增加相关的因素包括老年,糖尿病脏病,高血压脏病,晚期CKD阶段,平均动脉压升高和尿蛋白增加.
- 低血与ALVDD风险降低有关.
结论:
- 无症状的左心室扩张功能障碍在非透析的CKD患者中非常普遍.
- 密切监测和管理年龄,高血压,糖尿病,CKD进展,蛋白尿和水平至关重要.
- 早期发现和干预ALVDD可能有助于预防症状性HF的进展,并改善CKD患者的心血管结果.
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