释放患者的声音:赋权不良事件评估与完整的患者报告结果
Thi Hanh Phung1,2, Natalie Bradford1,3,4,5, Erin Pitt1,3
1School of Nursing, Faculty of Health, N block, Queensland University of Technology, Kelvin Grove, 4059, Australia.
The oncologist
|May 24, 2024
概括
在常规癌症护理中,每周完成患者报告结果的常见术语标准对不良事件 (PRO-CTCAE) 问卷是不可行的. 患者报告了高症状负担,这表明在化疗期间的症状评估存在挑战.
科学领域:
- 在瘤学瘤学.
- 患者报告的结果
- 临床试验方法论 临床试验方法论
背景情况:
- 在癌症临床试验中,患者报告的结果常见术语标准对不良事件 (PRO-CTCAE) 问卷对识别副作用至关重要.
- 尽管它的实用性,但在常规癌症护理环境中它的实施尚未得到充分探索.
- 在接受化疗的患者中评估症状负担是复杂的.
研究的目的:
- 在接受化疗的癌症患者中,研究每周在九周内每周完成PRO-CTCAE的可行性.
- 评估完成率,并确定与常规PRO-CTCAE使用相关的挑战.
主要方法:
- 一项前性研究涉及30名接受化疗的癌症患者.
- 参与者每周完成电子调查,持续9周,有提醒,但没有激励或反.
- 分析了124项PRO-CTCAE的完成率,评估了78种症状.
主要成果:
- 只有50%的计划中的PRO-CTCAE自我报告是完全完成的,另外8%是部分完成的.
- 患者报告的症状中位数为30种,有些人出现多达51种症状.
- 这表明未能达到预期的完成水平,并突出显著的症状负担.
结论:
- 在临床试验环境之外,在常规癌症护理中,每周实施PRO-CTCAE可能是不可行的.
- 这项研究强调了患者在化疗期间经历的广泛和复杂的症状.
- 需要进一步的研究来优化PRO-CTCAE在各种临床环境中的使用.
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