关于胃微生物群的当前知识,特别强调与Helicobacter pylori相关的胃疾病
Luigi Santacroce1, Skender Topi2, Lucrezia Bottalico2
1Section of Microbiology and Virology, Interdisciplinary Department of Medicine, School of Medicine, University of Bari 'Aldo Moro', 70124 Bari, Italy.
杆菌感染会破坏胃微生物群,导致炎症和潜在的癌症. 益生菌,益生菌和多在对抗H. pylori及其影响方面表现有前途.
科学领域:
- 微生物学 微生物学
- 胃肠病学 胃肠病学
- 免疫学 免疫学 免疫学
背景情况:
- 胃的酸性环境通常会抑制细菌的生长.
- 螺旋杆菌 (H.p.) 的 螺旋杆菌 (H.p.) 的 这一发现揭示了胃是微生物生命的港湾.
- 在H.P.的基础上. 使用毒素生存和损害胃粘膜,导致炎症和潜在的癌症.
研究的目的:
- 描述胃微生物群在健康和疾病中的组成.
- 为了澄清HP介导的细胞和分子损伤机制.
- 讨论益生菌,益生菌和多对抗HP的治疗潜力. 感染. 感染.
主要方法:
- 审查关于胃微生物群和H.p.的现有文献. 病变发生. 病变发生.
- 对H.p.的细胞和分子机制的分析. 伤害. 伤害. 这种伤害.
- 讨论涉及H.p.中的益生菌,益生菌,共生菌和多的研究. 感染模型和患者.
主要成果:
- 在H.P.的基础上. 感染诱导胃异位和慢性炎症,增加胃癌的风险.
- 益生菌和益生菌表明抗炎,抗氧化和抗菌作用对HP.
- 协生菌可以增强H.p. 在与常规疗法相结合时消除.
- 聚醇显示出缓解HP相关病理和抑制瘤发生的潜力.
结论:
- 在H.P.的基础上. 显著影响胃微生物群和健康.
- 益生菌,益生菌,共生菌和多醇为HP提供了有前途的治疗策略. 感染和相关疾病.
- 对这些天然化合物和微生物群调节的进一步研究是有必要的.
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