BACE1 APP/Aβ

James A Langeland1, Lillian Baumann1, Eva M DeYoung1

  • 1Department of Biology, Kalamazoo College, 1200 Academy Street, Kalamazoo, MI 49006, USA.

Biology
|May 24, 2024
PubMed
概括

涉及阿尔茨海默病的BACE1酶,可能在动物起源附近进化了其粉样蛋白前体蛋白 (APP) 和β-粉样蛋白 (Aβ) 分裂功能. 这种特定的蛋白质分解活性在它的基质APP进化之前出现了数亿年.

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