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Updated: Jun 25, 2025

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阐明微RNA-18a在推进混合上皮层-半细胞表型和驱动ER阴性乳腺癌恶性进展中的作用

Madhumathy G Nair1, Apoorva D Mavatkar1, Chandrakala M Naidu1

  • 1Division of Molecular Medicine, St. John's Research Institute, St. John's Medical College, Bangalore 560034, Karnataka, India.

Cells
|May 24, 2024
PubMed
概括

低的miR-18a表达在ER阴性乳腺癌中驱动了像迁移和茎状的侵略性特征. 这项微RNA (miRNA) 研究揭示了亚型在瘤进展和转移中的特定作用.

关键词:
有ER阴性乳腺癌的患者.化学电阻是一种化学电阻.表皮 mesenchymal 过渡的转变.混合的E/M表型是混合的.这是微RNA-18a.类似干细胞的干细胞.

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