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Updated: Jun 25, 2025

Techniques to Induce and Quantify Cellular Senescence
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诱导多能干细胞衍生纤维细胞有效地参与衰老路径,但对压力诱导物的敏感性增加

Marie-Lyn Goyer1,2, Cynthia Desaulniers-Langevin1,2, Anthony Sonn1,2

  • 1Centre de Recherche du CHU Sainte-Justine, 3175 Côte Sainte-Catherine, Montréal, QC H3T 1C5, Canada.

Cells
|May 24, 2024
PubMed
概括

诱导多能干细胞衍生纤维细胞 (i-HF) 维持DNA修复和衰老路径. 然而,i-HF表现出更高的应激敏感性和衰老,这可能会限制它们在细胞治疗中的使用.

关键词:
修复DNA的修复DNA的修复在 SASP 找 SASP由iPSC衍生的纤维细胞.衰老是一种老化.转化转化转化转化转化转化转化转化

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