不同铁制剂用于预防的使用以及对婴儿期铁状况的影响
Merve Tosyalı1, Yavuz Demirçelik2, Özlem Bağ3
1Department of Pediatrics, Faculty of Medicine, Ege University, Children's Hospital, 35100 Izmir, Turkey.
Healthcare (Basel, Switzerland)
|May 24, 2024
概括
铁盐在预防婴儿缺铁和缺铁性贫血方面比微封装或糖体铁制剂更有效. 定期使用铁和更高的社会经济地位与婴儿的铁状况更好有关.
科学领域:
- 儿科 儿科 儿科
- 营养科学 营养科学
- 血液学 血液学 血液学
背景情况:
- 缺铁和缺铁性贫血是婴儿健康的重大问题.
- 有各种铁制剂可用于预防,但它们对婴儿的比较疗效尚未完全确定.
研究的目的:
- 评估不同铁制剂在预防婴儿缺铁和/或缺铁性贫血方面的有效性.
- 评估这些制剂对婴儿铁状况的影响.
主要方法:
- 对651名9至13个月龄的健康婴儿的电子病历进行了回顾性评估.
- 根据使用的铁制剂类型 (Fe+3,Fe+2,微封装,糖体) 分析铁状况指标 (血红蛋白,血清铁,铁素).
主要成果:
- 与使用Fe+2或Fe+3盐的婴儿相比,使用糖体铁和微封装铁的婴儿显示出较低的血红蛋白,血清铁和铁素水平.
- 在31.9%的婴儿中诊断出铁缺乏症,使用糖体或微封装铁的婴儿的发病率更高.
- 定期补充铁和更高的家庭社会经济地位与较低的缺铁发病率有关.
结论:
- 铁盐 (Fe+2和Fe+3) 在预防婴儿缺铁和缺铁性贫血方面似乎比糖体或微封装铁制剂更有效.
- 虽然家庭可能更喜欢替代性准备,但铁盐在本研究中表现出更好的结果.
- 需要进行更多的随机对照试验,以确定不同铁制剂在婴儿铁预防中的有效性.
相关概念视频
Factors Affecting Drug Response: Overview
2.0K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.0K
Development of Immunocompetence
303
The initiation of cell-mediated immunity can be observed as early as the third month of fetal growth, with active antibody-mediated immunity following approximately one month later.
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
The initial cells that migrate from the fetal thymus settle within the skin and epithelial tissues lining the mouth, digestive tract, and in females, the uterus and vagina. These cells, including skin-based dendritic cells, serve as antigen-presenting cells, playing a key role in T cell activation.
Subsequent T...
303


