在非手术性牙周治疗中富含血小板纤维素:分口随机对照临床试验
Simran R Parwani1, Kaustubh S Thakare1, Kshipra P Kawadkar1
1Department of Periodontology, V.Y.W.S. Dental College and Hospital, Amravati 444602, India.
Dentistry journal
|May 24, 2024
概括
富含血小板纤维素 (PRF) 结合缩放和根平整 (SRP) 显著改善牙周健康. 这种辅助疗法增强了临床的附着效益,并比单独使用SRP更有效地减少了口袋深度.
科学领域:
- 牙周病学 牙周病学
- 恢复性牙科 恢复性牙科
背景情况:
- 非手术性牙周治疗,包括缩放和根平整 (SRP),是牙周疾病的标准护理.
- 富含血小板纤维素 (PRF) 是一种生物活性缩物,以其治疗特性而闻名.
研究的目的:
- 评估PRF作为SRP在非手术性牙周治疗中的辅助药物的疗效.
- 为了比较SRP与PRF和单独SRP之间的临床结果.
主要方法:
- 一个分口随机对照试验,涉及13名患者和26个牙周部位.
- 在试验场所,PRF被添加到SRP中;对照场所仅接受SRP.
- 评估了临床参数,包括探测口袋深度 (PPD),临床附着损失 (CAL),牙衰退 (GR),斑块指数,牙炎指数和伤口愈合指数.
主要成果:
- 与单独使用SRP的组相比,SRP+PRF组在CAL增益 (p=0.001) 和PPD减少 (p=0.001) 中呈现出统计学上显著的改善.
- 虽然SRP+PRF组显示了减少牙衰退的趋势 (p=0.21),但这种差异在统计学上并不显著.
- 辅助PRF增强了伤口愈合,减少了口袋深度,并将组织发病率降到最低.
结论:
- 作为SRP的辅助,PRF在治疗牙周口袋 (5-6毫米) 中是有效的.
- 这种方法可能会导致牙周关闭所需的牙周治疗疗程减少.
- 在改善非手术性牙周治疗的结果方面,PRF显示出前景.
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