预先消化的阿拉基酸和多可萨赫萨酸混合物,以提高生物可访问性
Assamae Chabni1, Blanca Pardo de Donlebún2, Marina Romero1
1Department of Production and Characterization of Novel Foods, Institute of Food Science Research (CIAL, CSIC-UAM), C/Nicolas Cabrera 9, Cantoblanco Campus, Autonomous University of Madrid, 28049 Madrid, Spain.
Marine drugs
|May 24, 2024
概括
开发了一种预消化的脂混合物,由阿拉基酸 (ARA) 和 docosahexaenoic 酸 (DHA) 组成. 这种产品表现出极好的生物可访问性,90%在体外消化后的细胞阶段被发现.
科学领域:
- 脂质化学和营养科学.
- 生物技术和食品加工.
背景情况:
- 阿拉基酸 (ARA) 和多可萨赫萨酸 (DHA) 是对婴儿发育和认知功能至关重要的必需脂肪酸.
- 优化ARA和DHA的输送和吸收对于营养应用很重要.
- 目前制备脂质补充剂的方法可能并不总是确保最佳的生物可用性.
研究的目的:
- 从ARA和DHA油中开发一种预消化的脂质产品,提高生物可访问性.
- 为了优化ARA和DHA的酶解水解和化过程.
- 评估开发的预消化脂质混合物的体外生物可访问性.
主要方法:
- 酶性水解ARA和DHA油,以获得90%的自由脂肪酸 (FFAs).
- 用糖醇对FFF进行酶性化,其ARA与DHA的比率为2:1 (w/w).
- 优化糖比率和温度 (10°C, 3:1糖与FA的摩尔比率).
- 在体外消化模型来评估生物可访问性.
主要成果:
- 一个预消化的ARA和DHA脂质混合物成功地产生了.
- 最佳条件涉及10°C和3:1的糖与FA摩尔比率.
- 在体外消化表明90%的产品在细胞阶段.
- 细胞阶段含有30%的单甘油,>50%的FFA和3%的三甘油.
结论:
- 开发的ARA和DHA预消化的脂质混合物在体外表现出极好的生物可访问性.
- 优化的酶过程产生了富含FFF和单糖的产品,有利于吸收.
- 这种预消化的产品具有营养应用的潜力,需要有效地输送ARA和DHA.
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