相关实验视频

Updated: Jul 30, 2026

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay
09:12

G Protein-selective GPCR Conformations Measured Using FRET Sensors in a Live Cell Suspension Fluorometer Assay

Published on: September 10, 2016

9.6K

基于计算机模拟和多种光谱方法,分析了三种 perfluorosulfonates 和 GPER 之间的结合模式

Wenhui Liang1, Yanting Chen1, Yuchen Wei1

  • 1College of Chemistry and Bioengineering, Guilin University of Technology, Guilin 541004, China.

Toxics
|May 24, 2024
PubMed
概括

perfluorinated compounds (PFCs) 强烈地与G蛋白结合雌激素受体 (GPER) 结合,改变了蛋白质的结构和稳定性. 这项研究澄清了PFCs.

关键词:
与G蛋白结合的雌激素受体受体分子对接的分子对接.分子动力学模拟模拟这是一种 perfluorochemical 的产品.频谱学是一种光谱学.

更多相关视频

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow09:04

Identifying Per- and Polyfluorinated Chemical Species with a Combined Targeted and Non-Targeted-Screening High-Resolution Mass Spectrometry Workflow

Published on: April 18, 2019

12.4K
Interfacial Molecular-level Structures of Polymers and Biomacromolecules Revealed via Sum Frequency Generation Vibrational Spectroscopy09:43

Interfacial Molecular-level Structures of Polymers and Biomacromolecules Revealed via Sum Frequency Generation Vibrational Spectroscopy

Published on: August 13, 2019

9.4K

相关概念视频

Conserved Binding Sites01:49

Conserved Binding Sites

Many proteins’ biological role depends on their interactions with their ligands, small molecules that bind to specific locations on the protein known as ligand-binding sites. Ligand-binding sites are often conserved among homologous proteins as these sites are critical for protein function.
Binding sites are often located in large pockets, and if their location on a protein’s surface is unknown, it can be predicted using various approaches. The energetic method computationally analyses the...