菌对口腔病原体的益生菌作用:一个体外研究
Claudia María Bedoya-Correa1, Santiago Betancur-Giraldo2, John Franco1,3
1GIOM Group, Faculty of Dentistry, Universidad Cooperativa de Colombia, Medellin 055421, Colombia.
Pathogens (Basel, Switzerland)
|May 24, 2024
概括
菌菌 (Streptococcus dentisani) 通过减少病原生物膜 (如Streptococcus mutans和Candida albicans) 来表现出益生菌的潜力. 这种口服益生菌通过排位和竞争策略有效地抑制生物膜的形成.
科学领域:
- 微生物学 微生物学
- 口腔健康 口腔健康
- 益生菌 益生菌 益生菌
背景情况:
- 益生菌正在探索恢复口腔微生物平衡并防止致病生物膜的发展.
- 牙杆菌 (Streptococcus dentisani) 正在研究其在口腔健康方面的潜在作用.
研究的目的:
- 评估Streptococcus dentisani与Streptococcus mutans,Streptococcus mitis和Candida albicans的生物膜之间的益生菌能力.
- 用竞争,排斥和移位策略来确定S. dentisani在抑制生物膜形成方面的有效性.
主要方法:
- 评估所有测试菌株的单种生物膜形成.
- 通过体外竞争,排除和位移测定,评估S. dentisani对S. mutans,S. mitis和C. albicans生物膜的益生菌潜力.
主要成果:
- 丹提萨尼 (S. dentisani) 的生物膜产量中等.
- 虽然竞争和排斥效应对S. mutans和S. mitis没有显著的影响,但S. dentisani通过移位显著减少了致病性链球菌生物膜.
- S. dentisani 显著抑制了 C. albicans 生物膜的形成,通过竞争和取代.
结论:
- 在体外,S. dentisani表现出益生菌特性,有利于减少潜在的致病生物膜.
- 需要进一步的研究来阐明S. dentisani抑制生物膜形成的具体机制.
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