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Updated: Jul 15, 2026

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在scRNA-Seq数据中用于单细胞聚类的图形规范非负矩阵因数分解

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    IEEE journal of biomedical and health informatics
    |May 24, 2024
    PubMed
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    本研究介绍了Sc-GNNMF,这是一种用于单细胞RNA测序 (scRNA-seq) 数据分析的无监督学习框架. 它通过使用图形调节的非负矩阵因子化优化数据来改善细胞聚类和标记基因提取.

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    RNA-seq03:21

    RNA-seq

    RNA sequencing, or RNA-Seq, is a high-throughput sequencing technology used to study the transcriptome of a cell. Transcriptomics helps to interpret the functional elements of a genome and identify the molecular constituents of an organism. Additionally, it also helps in understanding the development of an organism and the occurrence of diseases. 
    Before the discovery of RNA-seq, microarray-based methods and Sanger sequencing were used for transcriptome analysis. However, while microarray-based...