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使用个性化框架进行保护膜骨增大:一个可行性案例系列.

Shih-Cheng Wen, Muhammad Saleh, Abdusalam Alrmali

    The International journal of periodontics & restorative dentistry
    |May 24, 2024
    PubMed
    概括

    这项研究引入了一种用于指导骨再生 (GBR) 的新型框架 (TF),以增强大缺陷中的骨增强. TF设计促进了显著的水平和垂直骨增益,显示了可预测的骨再生的有希望的结果.

    科学领域:

    • 口腔和牙面部外科手术
    • 再生医学是一种再生医学.
    • 生物材料工程 生物材料工程

    背景情况:

    • 导向骨再生 (GBR) 在保持大骨缺陷的空间和血管化方面面临挑战.
    • 现有的GBR技术需要有效的解决方案,以实现可预测的水平和垂直骨增强.

    研究的目的:

    • 引入和评估一个原始的,定制的框架 (TF) 设计,用于在显著的水平骨缺陷中增强GBR.
    • 评估使用TFs与骨移植和原膜结合用于骨增强的可行性和结果.

    主要方法:

    • 一个可行性案例系列,涉及三名具有重大水平缺陷的患者,这些患者使用定制的框架进行治疗.
    • 放置一个50/50自移植和牛异种移植混合物,覆盖着一个原膜.
    • 在8个月通过重新进入手术和骨髓活检的组织形态测量分析评估骨增益.

    主要成果:

    • 平均水平骨增益为8.0 ± 1.0毫米,垂直骨增益为3.0 ± 0.0毫米.
    • 组织形态测量分析显示,42.8%的新重要骨,18.8%的残留移植颗粒,38.4%的骨髓样结构.
    • 在所有情况下都取得了成功的植入物安置和恢复.

    结论:

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    • 使用带有或没有原膜的框架的GBR似乎适合于水平和垂直的骨增强.
    • 定制的TF设计显示了在GBR中增强空间维护和可预测性的潜力.
    • 这一小案例系列的结果需要仔细解释和进一步调查.