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Updated: Jun 25, 2025

Quantification of Proteins Using Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry
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Quantification of Proteins Using Peptide Immunoaffinity Enrichment Coupled with Mass Spectrometry

Published on: July 31, 2011

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加博尔基于转换的信号隔离,快速解卷和质谱测量完整的蛋白质离子的量化

Kayd L Meldrum1, Andrew K Swansiger1, Meghan M Daniels1

  • 1Department of Chemistry and Biochemistry, University of Oregon, Eugene, Oregon 97403-1253, United States.

Analytical chemistry
|May 24, 2024
PubMed
概括

新的软件,即用于质谱学的交互式里埃变换分析 (iFAMS),使用加博变换 (GT) 增强了蛋白质量测量. 它提高了高分辨率质谱学中复杂的生物混合物的解卷客观性和可重现性.

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Mass spectrometry is an important technique for the identification of pure compounds. However, it has some limitations for the analysis of complex mixtures, often due to excessive fragmentation making the spectrum too complicated to decipher. Mass spectrometry can be combined with suitable separation methods in sequence, forming hyphenated methods, which are useful in the analysis of complex mixtures.
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