吸烟和重复流产:一项对2829名妇女的队列研究
Kathrine Vauvert R Hviid1, Sofie Bliddal2, Meryam El Issaoui3
1Recurrent Pregnancy Loss Unit, Capital Region, Copenhagen University Hospitals, Rigshospitalet Dept. Fertility & Hvidovre Hospital, Dept. of Obstetrics and Gynecology, Kettegaard Alle 30, Hvidovre DK-2650, Denmark; Dept. of Obstetrics and Gynecology, Hvidovre Hospital, Kettegaard Alle 30, Hvidovre DK-2650, Denmark.
Journal of reproductive immunology
|May 24, 2024
概括
吸烟的重复流产 (RPL) 妇女有更多的先前流产和死产. 虽然更少的人怀孕,但他们的活产率相似,但宫外怀孕和死产更为常见.
科学领域:
- 生殖医学 生殖医学
- 产科和妇科 产科和妇科
- 公共卫生 公共卫生
背景情况:
- 怀孕期间吸烟会对生殖结果产生负面影响.
- 吸烟或以前吸烟对重复流产 (RPL) 的妇女的影响不太清楚.
研究的目的:
- 调查当前吸烟和以前吸烟对重复流产 (RPL) 的妇女怀孕结果的影响.
主要方法:
- 一项队列研究包括2829名42岁以下的妇女,这些妇女被转到RPL单位 (2000-2022年).
- 患者被分为推时的吸烟者,从未吸烟者或前吸烟者.
- 结果包括怀孕史,潜在的怀孕率,活产率,宫外怀孕和死产.
主要成果:
- 推时的吸烟者比从未吸烟者更年轻,并且比从未吸烟者更容易失去怀孕和死产.
- 吸烟者 (71.8%) 与从未吸烟者 (77.5%) 的预期怀孕率较低.
- 活产率相似 (58.0%对61.4%),但死产 (2.8%对0.4%) 和宫外怀孕 (6.0%对2.0%) 在吸烟者中明显高.
结论:
- 患有RPL的妇女在转诊时吸烟,目前有更大的妊娠损失史.
- 虽然吸烟与转诊后怀孕的减少有关,但活产率与从未吸烟者相比相当.
- 妇女目前的吸烟与RPL增加死产和子宫外怀孕的风险.
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